Monoclonal Anti-CTNNB1 antibody produced in mouse,100UG,WH0001499M2-100UG,Sigma

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订货号 0BT8559
品牌型号 Sigma WH0001499M2-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the ′contact inhibition′ signal, which instructs cells to stop dividing once an epithelial sheet is complete.[supplied by OMIM


Immunogen

CTNNB1 (AAH58926, 682 a.a. ~ 781 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
LFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFHSGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTDL


Physical form

Solution in phosphate buffered saline, pH 7.4


Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone1C9, monoclonal
formbuffered aqueous solution
species reactivityhuman
technique(s)immunofluorescence: suitable,indirect ELISA: suitable,proximity ligation assay: suitable,western blot: 1-5 μg/mL
isotypeIgG2aκ
GenBank accession no.NM_001904
UniProt accession no.P35222
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... CTNNB1(1499)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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