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General description
Pivotal role of potassium channel is maintaining cell volume, membrane potential and neuronal excitability. Two families of potassium channel exists- one with inwardly rectifying potassium channel and the other with voltage sensing (KV) big conductance, calcium activated (BKCA ) small conductance and calcium activated (SK) potassium channel. KV1.5 channel is O2 sensitive, so hypoxia inhibits the expression of KV1.5 channel through 15-HETE pathway. Anti-Potassium Channel Kv1.5 antibody reacts specifically with full length Kv1.5 protein of rat and mouse.
Immunogen
GST fusion protein from the C-terminal of mouse potassium channel Kv1.5 corresponding to amino acids 513-602.
Application
Anti-Potassium Channel Kv1.5 antibody can be used in immunocytochemistry, immunoblotting and immunofluorescence.
Physical form
Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, 5% sucrose and 0.05% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | lyophilized powder |
| species reactivity | mouse, rat |
| technique(s) | western blot (chemiluminescent): 1:200-1:400 |
| web metadata keyword.default | Anti-Potassium Channel Kv1.5 antibody rabbit Sigma-Aldrich,KV1.5 (K-16) antibody rabbit,KV1.5 (M-110) antibody for Western blot,KV1.5 antibody Western blot chemiluminescent,KV1.5 channel antibody for hypoxia research,KV1.5 rabbit antibody,anti-KCNA5 antibody for neuronal studies,anti-Kv1.5 antibody 100µg,anti-Kv1.5 antibody 200µg Sigma-Aldrich,anti-Kv1.5 antibody for calcium activated channel research,chemiluminescent Western blot KV1.5 antibody,high purity anti-KV1.5 antibody for research,lab-grade Kv1.5 antibody for membrane potential studies,rabbit anti-KV1.5 antibody 1:200 dilution |
| UniProt accession no. | Q61762 |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | mouse ... Kcna5(16493) rat ... Kcna5(25470) |
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