- 商品介绍
- 规格参数
- 包装参数
General description
This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, specifically with histone H3 that is trimethylated at lysine 4. Mutations in this gene cause Omenn syndrome, a form of severe combined immunodeficiency associated with autoimmune-like symptoms.
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 258-527 of human RAG2 (NP_001230715.1).
Physical form
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | liquid |
| species reactivity | mouse, human, rat |
| concentration | 1.58 mg/mL |
| technique(s) | immunohistochemistry: 1:50-1:200,western blot: 1:500-1:2000 |
| UniProt accession no. | P55895 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... RAG2(5897) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
¥ 2013.69
-
¥ 5887.85
-
询价
-
询价
-
询价
-
询价
-
¥ 3152.47
-
询价
-
¥ 5167.58
-
¥ 2842.54
-
¥ 2666.57
-
¥ 2288.54
-
NALGENE 180透明塑料管，透明，柔软，多用，经济，内径 x 外径x壁厚，1/8 x 1/4 x 1/16，英寸，每箱数量50，50/箱，8000-0020，Thermofisher，赛默飞世尔询价
-
¥ 17652.29
-
¥ 58184.19
-
询价
-
询价
-
¥ 22137.02
-
¥ 57595.03
-
¥ 402833.12
微信小程序
7X24小时在线咨询