Anti-Phospho-PDGFRA-Y754 antibody produced in rabbit,100UL,SAB5700410-100UL,Sigma

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订货号 0BT9871
品牌型号 Sigma SAB5700410-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.


Immunogen

A synthetic phosphorylated peptide around Y754 of human PDGFRA (NP_006197.1).


Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.


Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wt 122, 24, 82
species reactivityhuman
concentration5.28 mg/ml
technique(s)western blot: 1:500-1:2000
UniProt accession no.P16234
shipped inwet ice
storage temp.−20°C
target post-translational modificationphosphorylation (pTyr754)
Gene Informationhuman ... PDGFRA(5156)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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