- 商品介绍
- 规格参数
- 包装参数
Immunogen
Synthetic peptide directed towards the N terminal region of human KCNQ2
Biochem/physiol Actions
The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by KCNQ2 and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in KCNQ2 are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1).
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: YRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFL
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 93 kDa |
| species reactivity | mouse, dog, horse, human, guinea pig, rat, bovine |
| concentration | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| web metadata keyword.default | Anti-KCNQ2 antibody rabbit Sigma-Aldrich,Anti-KCNQ2 antibody western blot application,Anti-Potassium voltage-gated channel KCNQ2 antibody,Anti-Potassium voltage-gated channel KCNQ2 for research,KCNQ2 antibody procurement for laboratory use,KCNQ2 antibody synthetic peptide region YRGWRGRLKFARKPFC,KCNQ2 antibody western blotting reagent,KCNQ2 antibody with sodium azide and sucrose,Sigma-Aldrich KCNQ2 antibody 1x PBS,anti-KCNQ2 antibody 0.09% sodium azide formulation,high-purity Anti-KCNQ2 antibody for research use,purified Anti-KCNQ2 antibody 1x PBS buffer,rabbit polyclonal Anti-KCNQ2 antibody,research grade Anti-KCNQ2 antibody for western blot,research use only Anti-KCNQ2 antibody from Sigma |
| NCBI accession no. | NP_004509 |
| UniProt accession no. | Q5VYT9 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... KCNQ2(3785) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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