Anti-Bak Antibody, clone 7Q3T8, Rabbit Monoclonal,100UL,SAB5702005-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BU2453
品牌型号 Sigma SAB5702005-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.


Immunogen

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Recombinant fusion protein containing a sequence corresponding to amino acids 11-82 of human Bak (NP_001179.1).


Application

WB, IHC


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
materialcolorless
clone7Q3T8, monoclonal
formliquid
mol wt 25 kDa
species reactivitymouse
concentration0.089 mg/mL
technique(s)immunohistochemistry: 1:50 - 1:100,western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceRQECGEPALPSASEEQVAQDTEEVFRSYVFYRHQQEQEAEGVAAPADPEMVTLPLQPSSTMGQVGRQLAIIG
UniProt accession no.Q16611
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... BAK1(578)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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