Anti-PYGM (C-term) antibody produced in rabbit，100UG，SAB1300187-100UG，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

Glycogen phosphorylase, muscle associated (PYGM) encodes glycogen phosphorylase or myophosphorylase. In human chromosome, the gene PYGM is localized on 11q13.1.

Immunogen

PYGM (NP_005600, 703-737)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PYGM.

Biochem/physiol Actions

PYGM catalyses and regulates the breakdown of glycogen to glucose-1-phosphate. Defects in PYGM are the cause of Glycogenosis type V/ glycogen storage disease type 5 (GSD5), also known as McArdle disease/ myophosphorylase deficiency, is an autosomal recessive disorder. GSD5 is a metabolic disorder resulting in myopathy characterized by exercise intolerance, cramps, muscle weakness and recurrent myoglobinuria.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	rabbit
Quality Segment	100
conjugate	unconjugated
antibody form	Ig fraction of antiserum
antibody product type	primary antibodies
clone	polyclonal
form	buffered aqueous solution
species reactivity	human
technique(s)	indirect ELISA: 1:1000,western blot: 1:100-1:500
NCBI accession no.	NP_005600
UniProt accession no.	P11217
shipped in	dry ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... PYGM(5837)

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