- 商品介绍
- 规格参数
- 包装参数
General description
c-KIT (T670I) is a protein that belongs to the type I cytokine receptor family which combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. c-KIT (T670I) is a good candidate gene and the mutation of this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. The gene encoding this protein is localized on human chromosome 4q12.
Biochem/physiol Actions
The protein has a role in melanocyte development.
Physical form
Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Preparation Note
After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.
Legal Information
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
| recombinant | expressed in baculovirus infected Sf9 cells |
| product line | PRECISIO® |
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| specific activity | 11.2-16.8 nmol/min·mg |
| mol wt | ~73 kDa |
| NCBI accession no. | NM_000222 |
| shipped in | dry ice |
| storage temp. | −70°C |
| Gene Information | human ... KIT(3815) |
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询价
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¥ 2068.25
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¥ 8293.41
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¥ 4404.38
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¥ 2842.54
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¥ 3852.13
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¥ 787.34
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¥ 3476.87
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¥ 954.17
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¥ 2888.88
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¥ 4476.05
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¥ 44224.19
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¥ 25008.19
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