- 商品介绍
- 规格参数
- 包装参数
General description
ITK (IL2-inducible T-cell kinase) is a member of the Tec family of tyrosine kinases. ITK is expressed in T-cells.
Biochem/physiol Actions
ITK (IL2-inducible T-cell kinase) is important for T-cell activation through the T-cell antigen receptor. Absence of ITK in T cells causes impairment in TCR (T cell receptor)-mediated actin polymerization, cell polarization and signaling events associated with cytoskeletal reorganization.
Physical form
Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
Legal Information
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
| recombinant | expressed in baculovirus infected Sf9 cells |
| Quality Segment | 200 |
| product line | PRECISIO® Kinase |
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| specific activity | 49-67 nmol/min·mg |
| mol wt | ~53 kDa |
| UniProt accession no. | Q08881 |
| shipped in | dry ice |
| storage temp. | −70°C |
| Gene Information | human ... ITK(3702) |
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询价
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¥ 1259.40
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¥ 1563.36
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¥ 9207.92
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¥ 3290.05
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¥ 3319.60
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¥ 1749.15
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¥ 1196.14
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¥ 5061.38
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¥ 787.34
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¥ 1351.48
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¥ 9909.51
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