Monoclonal Anti-KLRC3 antibody produced in mouse,100UG,WH0003823M1-100UG,Sigma

销售价: ¥ 4443.23 / 件
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订货号 0BU3348
品牌型号 Sigma WH0003823M1-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms. (provided by RefSeq)


Immunogen

KLRC3 (NP_002252, 132 a.a. ~ 240 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
GKERRTWEESLQACASKNSSSLLSIDNEEEMKFLASILPSSWIGVFRNSSHHPWVTINGLAFKHEIKDSDHAERNCAMLHVRGLISDQCGSSRIIRRGFIMLTRLVLNS


Physical form

Solution in phosphate buffered saline, pH 7.4


Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone3D5, monoclonal
formbuffered aqueous solution
species reactivityhuman
technique(s)indirect ELISA: suitable,western blot: 1-5 μg/mL
isotypeIgG2aκ
GenBank accession no.NM_002261
UniProt accession no.Q07444
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... KLRC3(3823)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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