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Biochem/physiol Actions
Apolipoprotein C-III (apoC-III) is central in regulating the metabolism of triglyceride-rich lipoproteins. It is an inhibitor of lipoprotein lipase (LPL).
Apolipoprotein C-III (apoC-III) is central in regulating the metabolism of triglyceride-rich lipoproteins. It is an inhibitor of lipoprotein lipase (LPL). Plasma levels of apoC-III are somewhat correlated to body mass index (BMI) and insulin sensitivity, and strongly correlated to levels of VLDL triglycerides. Reduced levels of apoC-III lead to higher fatty acid uptake of plasma triglycerides into adipose tissue.
Physical form
Solution in 10 mM ammonium bicarbonate.
| biological source | human plasma |
| Quality Level | 200 |
| assay | ≥95% (SDS-GE) |
| form | buffered aqueous solution |
| mol wt | 8.75 kDa |
| technique(s) | electrophoresis: suitable |
| UniProt accession no. | P02656 |
| storage temp. | −20°C |
| Gene Information | human ... APOC3(345) |
| 长度(mm) | |
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