Monoclonal Anti-SERPINC1 antibody produced in mouse,200UL,SAB1403580-200UL,Sigma

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订货号 0BU4070
品牌型号 Sigma SAB1403580-200UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. (provided by RefSeq)


Immunogen

SERPINC1 (AAH22309.1, 1 a.a. ~ 259 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MYSNVIGTVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAEPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK


Physical form

Clear solution


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formascites fluid
antibody product typeprimary antibodies
clone2B12, monoclonal
mol wtantigen ~54.6 kDa
species reactivityhuman
technique(s)indirect ELISA: suitable,western blot: 1:500-1:1000
isotypeIgG2bκ
NCBI accession no.BC022309
UniProt accession no.P01008
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... SERPINC1(462)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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