KD-Validated Anti Paraoxonase 2 Antibody, clone 24GB1035, Rabbit Monoclonal,1004G,SAB6012416-100UL,Sigma

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订货号 0BU4182
品牌型号 Sigma SAB6012416-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
We are committed to bringing you Greener Alternative Products. This product is a Design for Sustainability (DfS) developed product, which belongs to one of the four categories of greener alternatives. Click here to view its DfS scorecard.


Immunogen

A synthesized peptide corresponding to a sequence within amino acids 200-354 of human PON2 [NP_000296.2].


Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.


Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.


技术参数 Specifications
biological sourcerabbit (Monoclonal)
Quality Segment100
recombinantexpressed in HEK 293 cells
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clone 24GB1035, recombinant monoclonal
formbuffered aqueous glycerol solution
mol wt 39 kDa
species reactivityhuman
packagingvial of 1.5 mL
enhanced validationrecombinant expression
Learn more about Antibody Enhanced Validation
sustainabilityGreener Alternative Product
concentration1 mg/ml
technique(s)flow cytometry: 1:2000,western blot: 1:1,000-1:5,000
isotypeIgG
Ensembl | human accession no.ENSG00000105854
NCBI accession no.NP_000296.2
UniProt accession no.Q15165
greener alternative categoryDfS-Developed
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... PON2(5445)
长度(mm)
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