Monoclonal Anti-DCTN2 antibody produced in mouse,100UG,WH0010540M1-100UG,Sigma

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订货号 0BU8715
品牌型号 Sigma WH0010540M1-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. (provided by RefSeq)


Immunogen

DCTN2 (AAH00718, 302 a.a. ~ 401 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
DADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMKKLGK


Physical form

Solution in phosphate buffered saline, pH 7.4


Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone2G7, monoclonal
formbuffered aqueous solution
species reactivityhuman
technique(s)indirect ELISA: suitable,indirect immunofluorescence: suitable,western blot: 1-5 μg/mL
isotypeIgG1λ
GenBank accession no.BC000718
UniProt accession no.Q13561
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... DCTN2(10540)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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