Anti-NQO1 antibody produced in rabbit,100UL,SAB5700008-100UL,Sigma

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订货号 0BU9415
品牌型号 Sigma SAB5700008-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein′s enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer′s disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.


Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-274 of human NQO1 (NP_000894.1).


Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.


Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wt 26, 27, 30
species reactivityhuman, mouse
concentration1.42 mg/ml
technique(s)immunofluorescence: 1:50-1:200,western blot: 1:500-1:2000
UniProt accession no.P15559
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... NQO1(1728)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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