PRKX, active, GST tagged human,10UG,SRP5070-10UG,Sigma

销售价: ¥ 3866.08 / 件
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订货号 0BV0194
品牌型号 Sigma SRP5070-10UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

PRKX is a serine/threonine protein kinase that is closely related to the catalytic subunit of the cAMP-dependent protein kinase. PRKX regulates epithelial morphogenesis during mammalian kidney development and PRKX expression markedly activates migration of cultured renal epithelial cells in the presence of cAMP. Aberrant adult kidney expression of PRKX is found in autosomal dominant polycystic kidney disease. PRKX is involved in macrophage and granulocyte maturation. Abnormal recombination between PRKX and a related pseudogene on chromosome Y is a frequent cause of sex reversal disorder in XX males and XY females.


Physical form

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.


Preparation Note

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles


Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany


技术参数 Specifications
recombinantexpressed in baculovirus infected Sf9 cells
product linePRECISIO® Kinase
assay≥70% (SDS-PAGE)
formbuffered aqueous glycerol solution
specific activity127-173 nmol/min·mg
mol wt ~73 kDa
NCBI accession no.NM_005044
shipped indry ice
storage temp.−70°C
Gene Informationhuman ... PRKX(5613)
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高度(mm)
重量(kg)
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