Anti-Collagen XVII/COL17A1 Antibody, clone 8W2C8, Rabbit Monoclonal,100UL,SAB5702481-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BV1677
品牌型号 Sigma SAB5702481-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008]


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1300-1400 of human Collagen XVII/COL17A1 (Q9UMD9).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


Application

WB, IHC


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
materialcolorless
clone8W2C8, monoclonal
formliquid
mol wt 180 kDa
species reactivityhuman
concentration0.6 mg/mL
technique(s)immunohistochemistry: 1:50 - 1:200,western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGP
UniProt accession no.Q9UMD9
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... COL17A1(1308)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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