Anti-YBX1 antibody produced in rabbit,100UL,SAB5700257-100UL,Sigma

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订货号 0BV2852
品牌型号 Sigma SAB5700257-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes.


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human YBX1 (NP_004550.2).


Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.


Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wt 35
species reactivitymouse, human, rat
concentration0.29 mg/ml
technique(s)immunofluorescence: 1:50-1:200,immunohistochemistry: 1:100-1:200,western blot: 1:500-1:2000
UniProt accession no.P67809
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... YBX1(4904)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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