- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
IL-5 (interleukin-5) is a maturation and differentiation factor for eosinophils. Thus, it is associated with allergy and related disorders. IL-5 association with its receptor causes activation of MEK/ERK (mitogen activated protein kinase kinase/extracellular-regulated kinase), p38 MAPK (mitogen activated protein kinase) and JAK/STAT (Janus kinase/signal transducer and activator of transcription) pathways.
Interleukin-5 is a product of activated T lymphocytes and exhibits activity on eosinophils, B cells and thymocytes. Synonyms or biological activities attributed to IL-5 include: EDF (eosinophil differentiating factor), BCGF-II (B cell growth factor-II), TRF (T cell replacing factor), IgA-EF (IgA enhancing factor) and EO-CSF (eosinophil colony stimulating factor). Natural IL-5 is a 45-50 kDa dimeric glycoprotein, although glycosylation is not required for activity. Human and mouse IL-5 exhibit homology at the nucleotide and amino acid levels and show species cross-reactivity.
Physical form
Lypholized from 0.2 um filtered solution of PBS, pH 7.2 with 50 ug BSA.
| biological source | human |
| Quality Segment | 200 |
| recombinant | expressed in baculovirus infected Sf21 cells |
| assay | ≥97% (SDS-PAGE) |
| form | lyophilized powder |
| potency | 0.1-0.5 ng/mL ED50 |
| mol wt | 32-34 kDa |
| packaging | pkg of 5 μg |
| concentration | 0.5-10 ng/mL |
| technique(s) | cell culture | mammalian: suitable |
| impurities | endotoxin, tested |
| UniProt accession no. | P05113 |
| storage temp. | −20°C |
| Gene Information | human ... IL5(3567) |
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¥ 1596.77
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¥ 2290.21
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¥ 3109.49
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¥ 5887.85
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¥ 3812.28
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瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmSFCA滤膜，孔径0.2um,适合瓶颈尺寸45mm，12/箱，291-4520，Nalgene，Thermofisher，赛默飞世尔¥ 2856.42
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¥ 2573.97
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¥ 2882.02
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