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- 规格参数
- 包装参数
General description
A more active lysinal analog of Leupeptin (Cat. No. 108975). A more potent inhibitor of cathepsin B (IC50 = 4 nM) compared to leupeptin (IC50 = 310 nM).
Lysinal analog of Leupeptin (Cat. No. 108975). A more potent inhibitor of cathepsin B (IC50 = 4 nM) than of leupeptin (IC50 = 310 nM). Note: this peptide forms cyclic isomers.
Note: this peptide forms cyclic isomers.
Biochem/physiol Actions
Cell permeable: no
Primary Target
cathepsin B
Product does not compete with ATP.
Reversible: no
Target IC50: 4 nM against cathepsin B
Preparation Note
Following reconstitution aliquot and freeze (-70°C). Stock solutions are stable for up to 1 month at -70°C.
Other Notes
Ac-Leu-Val-lysinal
McConnell, R.M., et al. 1993. J. Med. Chem. 36, 1084.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
| Quality Segment | 100 |
| assay | ≥95% (HPLC) |
| form | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze |
| color | white |
| solubility | water: 1 mg/mL |
| shipped in | ambient |
| storage temp. | −70°C |
| 长度(mm) | |
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| 重量(kg) |
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