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General description
Shank is a novel family of postsynaptic density proteins (PSD) that bind to PDS-95-associated protein GKAP. Its putative function is to act as a scaffold protein in the PSD to cross-link NMDA receptors/PSD-95 complexes and couple them to regulators of the actin cytoskeleton. Shank1a is a splice variant of Shank1.
Immunogen
Epitope: N-terminus
Synthetic peptide corresponding to the N-terminus of rat Shank1a.
Application
Anti-SHANK1a Antibody, N-terminus is an antibody against SHANK1a for use in WB.
Research Category
Neuroscience
Research Sub Category
Synapse & Synaptic Biology
Western blotting: 1:500-1:1,000
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Recognizes Shank1a, N-terminal.
Physical form
Purified immunoglobulin. Liquid in PBS containing 0.02% sodium azide.
Format: Purified
Preparation Note
Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | polyclonal |
| species reactivity | rat |
| manufacturer/tradename | Chemicon® |
| technique(s) | western blot: suitable |
| NCBI accession no. | NM_016148.2 |
| UniProt accession no. | Q9Y566 |
| shipped in | dry ice |
| target post-translational modification | unmodified |
| Gene Information | rat ... Shank1(78957) |
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