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- 规格参数
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General description
Myb-binding protein 1A (MYBBP1A) interacts with sequence specific DNA-binding proteins in order to activate or repress transcription. Transcriptional repression via Myb-binding protein 1A is thought to be mediated by histone deacetylase activity (HDAC activity).
~160 kDa observed. Uncharacterized band(s) may be observed in some cell lysates. The full length of this protein is observed at ~160 kDa; however, it is proteolytically cleaved into ~140 kDa and ~67 kDa fragments (Hochstatter, J., et al. (2012). J Biol Chem. 287(29):24365-24377.; Mori, S., et al. (2012). PLoS One. 7(10):e39723.).
Immunogen
GST-tagged recombinant protein corresponding to human Myb Binding Protein 1A.
Application
Anti-Myb Binding Protein 1A Antibody is a highly specific rabbit polyclonal antibody, that targets Myb-binding protein 1A & has been tested in western blotting & ICC.
Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected Myb Binding Protein 1A in diploid human lung embryonic fibroblasts (Prof. Atilla Nemeth, University of Regensburg, Germany.).
Immunocytochemistry Analysis: A representative lot from an independent laboratory detected Myb Binding Protein 1A in HeLa cells (Hochstatter, J., et al. (2012). J Biol Chem. 287(29):24365-24377.).
Chromatin Immunoprecipitation (ChIP) Analysis: A representative lot from an independent laboratory immunoprecipitated Myb Binding Protein 1A in ChIP (Hochstatter, J., et al. (2012). J Biol Chem. 287(29):24365-24377.).
Biochem/physiol Actions
This antibody detects the full length and cleaved forms of Myb Binding Protein 1A.
Analysis Note
Evaluated by Western Blotting in A431 cell lysate.
Western Blotting Analyis: A 1:1,000 dilution from a representative lot detected Myb Binding Protein 1A in 10 µg of A431 cell lysate.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | serum |
| antibody product type | primary antibodies |
| clone | polyclonal |
| species reactivity | human |
| technique(s) | ChIP: suitable,immunocytochemistry: suitable,western blot: suitable |
| NCBI accession no. | NP_001099008 |
| UniProt accession no. | Q9BQG0 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... MYBBP1A(10514) |
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¥ 4164.19
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¥ 1259.40
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¥ 3109.49
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¥ 3152.47
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¥ 15214.65
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¥ 4404.38
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¥ 1568.60
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¥ 2617.87
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¥ 1476.00
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