- 商品介绍
- 规格参数
- 包装参数
General description
Calreticulin is a molecular Ca+ binding chaperone promoting folding, oligomeric assembly, and quality control in ER. Calreticulin is a highly versatile lectin-like chaperone, and it participates during the synthesis of a variety of molecules, including ion channels, surface receptors, integrins and transporters. Calreticulin indeed provides up to 45% of the Ca2+-buffering capacity for a pool of the IP3-sensitive Ca2+ inside the ER. Calreticulin also functions in cell adhesion, integrin-dependent Ca2+ signaling and steroid-sensitive gene expression.
~48 kDa observed
Immunogen
GST-tagged recombinant protein corresponding to human Calreticulin.
Application
Immunohistochemistry Analysis: A 1:300-1,000 dilution from a representative lot detected Calreticulin in human colorectal cancer and human tonsil tissues.
Flow Cyometry Analysis: A 1:500 dilution from a representative lot detected Calreticulin in non serum starved HeLa cells.
Research Category
Cell Structure
Research Sub Category
Adhesion (CAMs)
This Anti-Calreticulin Antibody, clone 16B11.1 is validated for use in Western Blotting, IHC, Flow Cytometry for the detection of Calreticulin.
Physical form
Format: Purified
Protein G Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
HeLa cell lysate
Evaluated by Western Blot in HeLa cell lysate.
Western Blot Analysis: A 1:1,000 dilution of this antibody detected Calreticulin on 10 µg of HeLa cell lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: MABT145
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | purified antibody |
| antibody product type | primary antibodies |
| clone | 16B11.1, monoclonal |
| species reactivity | human |
| technique(s) | flow cytometry: suitable,immunohistochemistry: suitable,western blot: suitable |
| isotype | IgG1κ |
| NCBI accession no. | NP_004334 |
| UniProt accession no. | P27797 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... CALR(811) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
询价
-
¥ 2707.32
-
询价
-
询价
-
询价
-
¥ 1956.41
-
询价
-
瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmSFCA滤膜，孔径0.2um,适合瓶颈尺寸45mm，12/箱，291-4520，Nalgene，Thermofisher，赛默飞世尔¥ 2856.42
-
¥ 4404.38
-
¥ 5061.38
-
¥ 787.34
-
¥ 954.17
-
¥ 2911.61
-
¥ 9909.51
-
¥ 4476.05
-
¥ 44224.19
-
¥ 145427.01
-
¥ 18741.69
-
询价
-
¥ 21144.84
微信小程序
7X24小时在线咨询