MILLIPLEX® Human High Sensitivity T Cell Panel，96WELLS，HSTCMAG28SPMX21，密理博

General description

Cytokines are immunomodulatory polypeptides that play key roles in both adaptive and innate immune responses. One of the regulatory mechanisms of the immune system, cytokines act at the recognition, activation, or effector phases of an immune response, modulating the development and functional activities of the subtypes of T cells, B cells and myeloid cells. Consequently, research involving cytokines plays a significant role in achieving a deeper understanding of the immune system and its multi-faceted response to most antigens, especially those responses that make up the inflammatory process. Low levels of inflammation are involved in many sub-clinical disease states, such as autoimmune disease, cardiovascular disease, diabetes, neurological disorders, and cancer. Measuring picogram levels of cytokines, therefore, is critical for understanding the pathogenesis of these diseases.

Application

MILLIPLEX^® Qualified assays undergo rigourous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 21 analytes in human serum, plasma, and cell culture supernatants.

Analytes included: Fractalkine/CX3CL1, GM-CSF, IFN-gamma, IL-1beta, IL-2, IL-4, IL-5, IL-6, IL-7, IL8/CXCL8, IL-10, IL-12 (p70), IL-13, IL17A/CTLA8, IL-21, IL-23, ITAC/EXCL11, MIP-1α/CCL3, MIP-1β/CCL4, MIP-3α/CCL20 and TNFα.

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

• Multiplex Capability: Simultaneous quantification of up to 21 cytokines and chemokines in a single sample using Luminex^® xMAP^® technology.
• High Sensitivity: Detects cytokines at picogram levels (as low as 0.11 pg/mL), ideal for low-abundance targets in serum, plasma, and cell culture supernatants.
• Comprehensive Coverage: Includes key T cell-related cytokines such as IL-2, IL-4, IL-10, IL-17A, IFNγ, TNFα, and more.
• Neuroimmune Axis Coverage: Includes IL-6 and MIP-1β, implicated in neuroinflammatory disorders, allowing you to decipher cytokine roles in Alzheimer’s, depression, or stroke recovery.
• Metabolic Inflammation Markers: Quantify IL-1β and IL-13, linked to insulin resistance and adipose inflammation to study obesity-driven metabolic syndrome or type 2 diabetes mechanisms.

Legal Information

Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.