- 商品介绍
- 规格参数
- 包装参数
General description
50 kDa
ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form autophagosomes. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. Conjugation to ATG12 is essential for autophagy, but is not required for association with isolation membrane. ATG5 also plays an important role in the apoptotic process. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity
Immunogen
Linear Peptide, aa: 8-318
Application
Immunoprecipitation: HeLa cell lysate
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
This Anti-ATG5 Antibody, clone 177.19 is validated for use in WB, IP for the detection of ATG5.
Biochem/physiol Actions
Other species have not been tested.
The antibody reacts with the 50 kDa ATG5 protein.
Physical form
Format: Purified
Protein G Purified
Purified in 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
Western Blot and Immunoprecipitation: HeLa cell lysate.
Western Blot Analysis: 0.5 ug/mL of this antibody detected ATG5 on HeLa cell lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: MABC137
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | purified antibody |
| antibody product type | primary antibodies |
| clone | 177.19, monoclonal |
| species reactivity | human |
| technique(s) | immunoprecipitation (IP): suitable,western blot: suitable |
| isotype | IgG2bκ |
| NCBI accession no. | NM_004849.2 |
| UniProt accession no. | Q9H1Y0 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... ATG5(9474) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
询价
-
询价
-
¥ 1866.29
-
¥ 8293.41
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
¥ 2883.61
-
¥ 1196.00
-
¥ 4020.77
-
¥ 67162.32
-
¥ 29754.56
-
¥ 25801.21
-
¥ 57595.03
-
¥ 57595.03
-
询价
-
询价
微信小程序
7X24小时在线咨询