Thrombin-Activatable Fibrinolysis Inhibitor, Human,50UG,605197-50UGCN,Sigma

销售价: ¥ 6854.03 / 件
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订货号 0BV4465
品牌型号 Sigma 605197-50UGCN
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Native thrombin-activatable fibrinolysis inhibitor from human liver. Single chain glycoprotein synthesized in the liver. ctivated by the thrombin/thrombomodulin complex by proteolytic cleavage at Arg92. Circulates in plasma as a zymogen at a concentration of about 50 nM. Believed to play an important role in the interaction between procoagulant, anticoagulant, and fibrinolytic systems.


Packaging

Please refer to vial label for lot-specific concentration.


Physical form

In 150 mM NaCl, 20 mM HEPES, pH 7.4.


Preparation Note

Following initial thaw, aliquot and freeze (-70°C).
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.


Other Notes

Boffa, M.B., et al. 1999. Biochemistry 38, 6547.
Boffa, M.B., et al. 1998. J. Biol. Chem. 273, 2127.
Bajzar, L., et al. 1995. J. Biol. Chem. 270, 14477.
One unit is defined as the amount of enzyme that will hydrolyze 1 µM Hip-L-Arg per min at 25°C, pH 7.65.


Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany


Disclaimer

Toxicity: Standard Handling (A)


技术参数 Specifications
Quality Level100
assay≥95% (SDS-PAGE)
formliquid
specific activity2-9 units/mg protein
manufacturer/tradenameCalbiochem®
storage conditionOK to freeze
shipped inwet ice
storage temp.−70°C
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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