BioTracker IRI-1 b-Amyloid Plaque Live Cell Dye，1MG，SCT067，Sigma

销售价： ¥ 3904.65 / 件

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订货号： 0BV4599

品牌型号： Sigma SCT067

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最小订货量： 1件

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产品介绍 Product Description

General description

Alzheimer′s disease (AD) is a common progressiveneurodegenerative disease eventually leading to fatality.Significant accumulation of pathological proteinaceous depositsin the brain, including Aβ plaques, are present decades beforesymptoms can be perceived. As such, the delay betweenpathological brain chemistry changes and symptoms creates awindow of opportunity for potential treatments.BioTracker IRI-1 b-Amyloid plaque live cell dye is a near-infrared-emissive two-photon microscopy (TPM) dye with high affinity for Aβ-fibrils. The dye demonstrates a ~167-fold increase in fluorescence in the presence of Aβ-fibrils. SCT067 achieves this while maintaining large two-photon cross-section, a large signal to background ratio, high BBB permeability, and emission reaching into the near-infrared (NIR, 650 nm). This dye has been used for ex-vivo and in vivo TPM imaging of Aβ-fibrils in mouse brains. Spectral Properties:For Two-photon microscopy.Excitation: 850 nmEmission: 580- 779 nmResearch Categories:Alzheimer′s DiseaseAutoimmune diseaseLive Cell DyeNeurodegenerative DiseasesNeurofilament & Neuron MetabolismNeuroscience

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Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial

技术参数 Specifications

form	lyophilized
detection method	fluorometric

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