- 商品介绍
- 规格参数
- 包装参数
General description
Approx. 50 kDa
GLUT-8 is a glucose transporter facilitated by the regulation of insulin, binding cytochalasin B such that the orientation is glucose-inhibitive. In appearance, the transporter seems to be a dual-specific sugar transporter since fructose can also be inhibitive. GLUT-8 is expressed largely in the testis, where down-regulation is facilitated by estrogen. However, GLUT-8 is not highly expressed in testicular carcinoma. Lower levels of GLUT-8 are present in most other tissues.
Immunogen
An 11 amino acid sequence near the C-terminus of mouse Glut-8 (Doege et al. 2000; Carayannopoulos et al. 2000)
Epitope: C-terminus
Application
Anti-GLUT-8 Antibody, C-terminus detects level of GLUT-8 & has been published & validated for use in IH(P).
Research Category
Signaling
Research Sub Category
Insulin/Energy Signaling
Biochem/physiol Actions
Recognizes GLUT-8.
Physical form
Format: Purified
ImmunoAffinity Purified
Liquid in PBS with 0.1% BSA.
Preparation Note
Maintain at -20°C in undiluted aliquots for up to 1 year from date of receipt. Avoid repeated freeze/thaw cycles.
Analysis Note
Control
Human kidney tissue.
Evaluated by Immunohistochemistry in human kidney tissue
Immunohistochemistry Analysis: 1:100 dilution of this lot detected GLUT-8 in human kidney tissue.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: AB3140
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| species reactivity | human |
| species reactivity (predicted by homology) | mouse |
| technique(s) | immunohistochemistry: suitable (paraffin) |
| UniProt accession no. | Q9NY64 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... SLC2A8(29988) mouse ... Slc2A8(56017) |
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