Anti-EGFR Antibody, neutralizing, clone LA1, Alexa Fluor™ 488,125UG,16-246,Sigma

销售价: ¥ 3519.77 / 件
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订货号 0BV5191
品牌型号 Sigma 16-246
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Included Negative Control: Catalog # 16-240, Alexa Fluor 488-conjugated Normal Mouse IgG.

Inhibits A431 cell growth. Recognizes an antigenic determinant located on the extracellular domain of the receptor.


Immunogen

Human A431 membrane proteins


Application

Research Category
Signaling
Research Sub Category
Growth Factors & Receptors
This Anti-EGFR Antibody, neutralizing, clone LA1, Alexa Fluor 488 is validated for use in IF for the detection of EGFR.


Biochem/physiol Actions

external domain of EGF receptor on all human cells. Competes with EGF and TGF-α for binding on human cells. Recognizes both phosphorylated and non-phosphorylated human EGF receptors.


Preparation Note

1 year at 4°C from date of shipment


Analysis Note

Routinely evaluated by positive immunostaining for the EGF receptor in A431 cells.


Legal Information

ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany


Disclaimer

Alexa Fluor is a registered trademark of Molecular Probes, Inc.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcemouse
Quality Level100
conjugateALEXA FLUOR 488
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
cloneLA1, monoclonal
species reactivityhuman, mouse, rat
manufacturer/tradenameUpstate®
technique(s)immunofluorescence: suitable
isotypeIgG1
NCBI accession no.NM_005228.3,NM_201282.1,NM_201283.1,NM_201284.1
UniProt accession no.P00533
shipped inwet ice
target post-translational modificationunmodified
Gene Informationhuman ... EGFR(1956)
mouse ... Egfr(13649)
rat ... Egf(25313)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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