- 商品介绍
- 规格参数
- 包装参数
General description
Included Negative Control: Catalog # 16-240, Alexa Fluor™ 488-conjugated Normal Mouse IgG.
Inhibits A431 cell growth. Recognizes an antigenic determinant located on the extracellular domain of the receptor.
Immunogen
Human A431 membrane proteins
Application
Research Category
Signaling
Research Sub Category
Growth Factors & Receptors
This Anti-EGFR Antibody, neutralizing, clone LA1, Alexa Fluor 488 is validated for use in IF for the detection of EGFR.
Biochem/physiol Actions
external domain of EGF receptor on all human cells. Competes with EGF and TGF-α for binding on human cells. Recognizes both phosphorylated and non-phosphorylated human EGF receptors.
Preparation Note
1 year at 4°C from date of shipment
Analysis Note
Routinely evaluated by positive immunostaining for the EGF receptor in A431 cells.
Legal Information
ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Alexa Fluor™ is a registered trademark of Molecular Probes, Inc.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Level | 100 |
| conjugate | ALEXA FLUOR™ 488 |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | LA1, monoclonal |
| species reactivity | human, mouse, rat |
| manufacturer/tradename | Upstate® |
| technique(s) | immunofluorescence: suitable |
| isotype | IgG1 |
| NCBI accession no. | NM_005228.3,NM_201282.1,NM_201283.1,NM_201284.1 |
| UniProt accession no. | P00533 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... EGFR(1956) mouse ... Egfr(13649) rat ... Egf(25313) |
| 长度(mm) | |
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