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- 规格参数
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General description
PP2A is a heterotrimeric phosphatase, ccomposed of A, B and C subunits. The structural A and catalytic C subunits form the constitutive core of the enzyme, which associates with one of a large number of regulatory B subunits. Three families of B subunits have been identified thus far. The prototypical B (or PR55) family of subunits is encoded by three genes, Balpha, Bbeta and Bgamma . The B′ (or B56) family consists of at least seven splice variantsderived from five genes. RNA′s for the two members of the B′′ family, PR72 and PR130, arise by alternative splicing or use of alternate transcription start sites from the same gene. Primary structures as well as functions of B and B′ subunits are conserved from yeast to mammals.
Immunogen
GST fusion protein corresponding to the N-terminus of human PP2A, B subunit, B56 delta
Application
Immunoblotting (1:500 to 1:2000)
Optimal working dilutions must be determined by the end user
Research Category
Signaling
Research Sub Category
Kinases & Phosphatases
This Anti-PP2A Antibody, B subunit, B56 delta, clone H5D12 is validated for use in WB for the detection of PP2A.
Biochem/physiol Actions
Human PP2A, B subunit, B56 delta. This monoclonal antibody is the delta isoform for the B56 family of protein phosphatase 2A.
Physical form
Format: Purified
Purified mouse monoclonal IgG1 antibody in PBS with 0.05% NaN3.
Preparation Note
Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | H5D12, monoclonal |
| species reactivity | human |
| manufacturer/tradename | Upstate® |
| technique(s) | western blot: suitable |
| isotype | IgG1 |
| NCBI accession no. | NM_006245 |
| UniProt accession no. | Q14738 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... PPP2R5D(5528) |
| 长度(mm) | |
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NALGENE 180透明塑料管，透明，柔软，多用，经济，内径 x 外径x壁厚，1/8 x 1/4 x 1/16，英寸，每箱数量50，50/箱，8000-0020，Thermofisher，赛默飞世尔
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