- 商品介绍
- 规格参数
- 包装参数
General description
DLL3, also known as Delta like ligand 3, is a transmembrane Delta-like protein principally found in the Golgi apparatus and endosomes where it promotes Notch family receptor degradation to inhibit primary neurogenesis. DLL3 is one of five DSL proteins that bind to the Notch receptor. Notch signaling pathways play key roles in cell-fate determination and differentiation in many tissues during embryonic and postnatal development. Notch ligands family members are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in the DLL3 gene causes autosomal recessive spondylocostal dysostosis.
~65 kDa observed
Immunogen
Linear peptide corresponding to human Delta3.
Application
Flow Cytometry Analysis: 0.1 µg from a representative lot detected Delta3 in HEK293 cells.
Research Category
Cell Structure
Research Sub Category
ECM Proteins
This Anti-Delta3 Antibody, clone 1E7.2 is validated for use in WB, FC for the detection of Delta3.
Physical form
Format: Purified
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
Human liver tissue lysate
Evaluated by Western Blot in human liver tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Delta3 on 10 µg of human liver tissue lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | 1E7.2, monoclonal |
| species reactivity | human |
| technique(s) | flow cytometry: suitable,western blot: suitable |
| isotype | IgMκ |
| NCBI accession no. | NP_058637 |
| UniProt accession no. | Q9NYJ7 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... DLL3(10683) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
¥ 3442.25
-
¥ 1956.41
-
询价
-
询价
-
无菌，PETG 方形有刻度培养基瓶，带盖，聚对苯二酸乙二醇酯共聚物，天然高密度聚乙烯盖，500毫升容量，每箱40，40/箱，342020-0500，Nalgene，Thermofisher，赛默飞世尔¥ 3684.34
-
¥ 2573.97
-
¥ 3852.13
-
¥ 1783.21
-
¥ 2132.12
-
¥ 3404.94
-
¥ 5990.26
微信小程序
7X24小时在线咨询