Carboxy-PTIO, Sodium Salt,10MG,217386-10MGCN,Sigma

销售价: ¥ 2402.41 / 件
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订货号 0BV5510
品牌型号 Sigma 217386-10MGCN
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Reacts with nitric oxide at pH 7.4, resulting in the generation of NO2-/NO3- with a rate constant of 1 x 104 M-1sec-1. Prevents SIN-1 induced endothelial cell death. Reported to have potent therapeutic value in endotoxin shock through its nitric oxide scavenging action.


Biochem/physiol Actions

Cell permeable: no
Primary Target
Nitric oxide scavenging action
Product does not compete with ATP.
Reversible: no


Packaging

Packaged under inert gas


Preparation Note

Following reconstitution, refrigerate (4°C). Aqueous stock solutions are stable for up to 1 week at 4°C.


Other Notes

Ishii, M., et al., 1999. J. Cardiovasc. Pharmacol. 33, 295.
Amano, F., and Nova, J. 1995. FEBS Lett.368, 425.
Hogg, N., et al. 1995. Free Radical Res.22, 47.
Az-ma, T., et al. 1994. Life Sci.54, 185.
Yoshida, M., et al. 1994. Biochem. Biophys. Res. Commun.202, 923.
Akaike, T., et al. 1993. Biochemistry32, 827.
Yoshida, K., et al. 1993. Infect. Immun.61, 3552.


Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany


Disclaimer

Toxicity: Standard Handling (A)


技术参数 Specifications
Quality Segment100
assay≥97% (TLC)
formsolid
manufacturer/tradenameCalbiochem®
storage conditionOK to freeze,desiccated (hygroscopic),protect from light
colordark blue
solubilityHEPES Buffer: 0.4 mg/mL
shipped inambient
storage temp.−20°C
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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