Anti-mGluR5 Antibody, clone 11D9.1,100UG,MABN139,Sigma

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订货号 0BV5541
品牌型号 Sigma MABN139
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Metabotropic glutamate receptor 5 (mGluR5) is a member of the G-protein coupled receptor family and functions as a receptor for glutamate. mGluR5 activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current.
~150 kDa observed. The calculated molecular weight is 130 kDa, however mGluR5 has been shown as a ~150 kDa band in western blots (Romano, C., et al. (1996). J Biol Chem. 271(45):28612-28616).


Immunogen

GST-tagged recombinant protein corresponding to human mGluR5.


Application

Detect mGluR5 using this mouse monoclonal antibody, Anti-mGluR5 Antibody, clone 11D9.1 validated for use in western blotting & IHC.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected mGluR5 in normal human brain tissue.


Physical form

Format: Purified


Analysis Note

Control
Rat brain micropreparation tissue lysate
Evaluated by Western Blotting in rat brain micropreparation tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected mGluR5 in 10 µg of rat brain micropreparation tissue lysate. The lysate was not boiled during preperation for western blotting.


Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone11D9.1, monoclonal
species reactivityhuman, rat
technique(s)immunohistochemistry: suitable,western blot: suitable
isotypeIgG2bκ
NCBI accession no.NP_000833
UniProt accession no.P41594
shipped inwet ice
target post-translational modificationunmodified
Gene Informationhuman ... GRM5(2915)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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