MILLIPLEX® Humanized Mouse Panel，1ST，HUMU-210K-PMX，Sigma

General description

Humanized mouse research has emerged as a pivotal tool in biomedical science, bridging the gap between preclinical studies and human disease. By engrafting human tissues, cells, or genes into immunocompromised mice, researchers can create models that more accurately mimic human immune responses and disease mechanisms. This innovative approach enhances the relevance of immunoassays, which are critical for evaluating immune function, disease progression, and therapeutic efficacy. As the demand for more predictive models in drug development and disease research grows, humanized mice are proving invaluable for advancing our understanding of human biology and improving therapeutic strategies.

Application

MILLIPLEX^® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 41 analytes in humanized mouse serum, plasma, and cell culture supernatants.
Human-specific analytes included: G-CSF, GM-CSF, IFNɣ, IL-1α, IL-1β, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-12p40, IL-12p70, IL-15, IL-17A, IL-18, IL-10, M-CSF, MCP-1, MIG, IP-10, TNFα
Mouse-specific analytes included: G-CSF, GM-CSF, IFNɣ, IL-1β, IL-2, IL-3, IL-5, IL-6, KC, IL-12p40, IL-12p70, IL-17A, IL-18, M-CSF, MCP-1, MIG, IP-10, TNFα
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

• Hassle-Free Premixed Bead Solutions: Premixed beads simplify your assay setup by reducing preparation time.
• Exclusive Market Offering: The only humanized mouse multiplex panel available on the market. Gain exclusive access to advanced research capabilities that provide unique insights, enhancing the value of your studies.
• Dual Species Assay: Simultaneously analyze human and mouse targets to study immune responses in mouse models.
• Minimal Sample Volume Requirement: Requires only 10 µL of sample volume per well. Economical use of precious samples, allowing for more experiments or tests to be conducted with limited sample availability.
• Proven Reliability and Accuracy: Ensure reproducibility and confidence in your results, which is critical for your research and pre-clinical applications.
• Ethical Research: Reduces animal use by enabling longitudinal studies without sacrifice.

Legal Information

Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.