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General description
SAP90/PSD-95-associated protein 2 (SAPAP2, also known as DLGAP2) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP2 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2).
~114 kDa observed. Uncharacterized bands may be observed.
Immunogen
KLH-conjugated linear peptide corresponding to human SAPAP2.
Application
Immunohistochemistry Analysis: 5 µg/mL of this antibody from a representative lot detected SAPAP2 in human brain tissue.
Research Category
Neuroscience
Research Sub Category
Synapse & Synaptic Biology
This SAPAP2 antibody is validated for use in WB & IHC for the detection of the SAPAP2 protein.
Biochem/physiol Actions
At least three isoforms of SAPAP2 are known to exist. This SAPAP2 antibody will not cross-react with other SAPAP proteins.
Physical form
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS and 0.02% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
L1210 cell lysate
Evaluated by Western Blot in L1210 cell lysate.
Western Bloting Analysis: 1 µg/mL of this antibody detected SAPAP2 in 15 µg of L1210 cell lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| purified by | affinity chromatography |
| species reactivity | mouse, human |
| technique(s) | immunohistochemistry: suitable,western blot: suitable |
| UniProt accession no. | Q9P1A6 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... DLGAP2(9228) |
| 长度(mm) | |
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