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Prion Protein, His•Tag®, Human, Recombinant, E. coli，100UG，530006-100UGCN，Sigma

销售价： ¥ 6124.75 / 件

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订货号： 0BV6992

品牌型号： Sigma 530006-100UGCN

货期：询货期

最小订货量： 1件

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商品介绍
规格参数
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产品介绍 Product Description

General description

Recombinant, human prion protein (amino acids 23-231) fused to a His•Tag sequence and expressed in E. coli. Prion diseases or transmissible spongiform encephalopathies are neurodegenerative diseases that affect both humans and animals. All prion diseases share the same molecular pathogenic mechanism that involves conversion of normal cellular prion protein (PrPc) into a form that is insoluble in non-ionic detergent and partially resistant to proteases (PrPsc). Useful as an antigen standard in immunochemical detection of Creutzfeldt-Jakob Disease (CJD).

Physical form

In 10 mM sodium acetate, pH 4.0.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Calzolai, L., and Zahn, R. 2003. J. Biol. Chem.278, 35592.
Prusiner, S.B. 1998. Proc. Natl. Acad. Sci. USA95, 13363.
Swietnicki, W., et al. 1997. J. Biol. Chem.272, 27517.
Pan, K.M., et al. 1993. Proc. Natl. Acad. Sci. USA90, 10962.
Basler, K., et al. 1986. Cell46, 417.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

技术参数 Specifications

assay	≥95% (SDS-PAGE)
Quality Level	100
form	liquid
manufacturer/tradename	Calbiochem^®
storage condition	OK to freeze,avoid repeated freeze/thaw cycles
shipped in	wet ice
storage temp.	−20°C

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