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General description
Galectin-3 belongs to the galectin gene family, which is defined by the specificity of a carbohydrate recognition domain (CRD) for Gal/Lac. Galectin-3 expression is usually elevated in a wide range of neoplastic cell types. The galectin CRD consists of 135 amino acids. Galectin-3 is known to play a role in tumor development, apoptosis, and cell cycle progression.
~33 kDa observed
Immunogen
Epitope: Pro64 mutation domain
KLH-conjugated linear peptide corresponding to the Pro64 mutation domain of human Galectin-3.
Application
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
This Anti-Galectin-3 Antibody is validated for use in WB for the detection of Galectin-3.
Biochem/physiol Actions
This antibody recognizes the Pro64 mutation domain of Galectin-3. It is equally specific for wild-type or mutant His64 Galectin-3.
Physical form
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
MG-63 cell lysate
Evaluated by Western Blot in MG-63 cell lysate.
Western Blot Analysis: A 1:250 dilution of this antibody detected Galectin-3 in 10 µg of MG-63 cell lysate.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| purified by | affinity chromatography |
| species reactivity | rhesus macaque, human |
| species reactivity (predicted by homology) | rhesus monkey (based on 100% sequence homology) |
| technique(s) | western blot: suitable |
| NCBI accession no. | NP_002297 |
| UniProt accession no. | P17931 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... LGALS3(3958) |
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¥ 2019.57
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¥ 8520.40
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¥ 8135.09
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¥ 6330.00
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¥ 4897.21
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