TRAIL, Human, Recombinant, E. coli,100UG,616374-100UGCN,Sigma

销售价: ¥ 6374.64 / 件
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订货号 0BV7457
品牌型号 Sigma 616374-100UGCN
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Recombinant, human TRAIL (amino acids 114-281) expressed in E. coli. Ligand for TRAIL receptors DR4 and DR5. Displays potent antitumor activity against selected targets and induces apoptosis in a number of transformed cell lines, but not in normal tissues.


Biochem/physiol Actions

Induces apoptosis in U937 cells at 1 μg/ml within 5 h.


Packaging

Please refer to vial label for lot-specific concentration.


Physical form

In 500 mM NaCl, 10 mM Na₂HPO₄, 2.7 mM KCl, 2 mM KH₂PO₄, 0.1 mM DTT, ≤10% glycerol.


Preparation Note

Following initial thaw, aliquot and freeze

(-70°C).


Other Notes

Lin, Y., et al. 2000. Mol. Cell. Biol.20, 6638.
Mitsaides, N., et al. 2000. Cancer Res.60, 4122.
Griffith, T.S., et al. 1999. J. Exp. Med.189, 1343.
Mariani, S.M., et al. 1997. J. Cell Biol.137, 221.
Pan, G., et al. 1997. Science276, 111.
Pan, G., et al. 1997. Science277, 815.
Sheridan, J.P., et al. 1997. Science277, 818.
Pitti, R.M., et al. 1996. J. Biol. Chem.271, 12687.
Wiley, S.R., et al. 1995. Immunity3, 673.


Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany


Disclaimer

Toxicity: Standard Handling (A)


技术参数 Specifications
assay≥95% (SDS-PAGE)
Quality Segment100
formliquid
manufacturer/tradenameCalbiochem®
storage conditionOK to freeze,avoid repeated freeze/thaw cycles
impurities<0.1 EU/μg endotoxin (EU/μg TRAIL)
shipped inwet ice
storage temp.−70°C
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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