- 商品介绍
- 规格参数
- 包装参数
General description
Signal-induced proliferation associated-like protein 1 (SIPA1L1), also called High-risk human papilloma viruses E6 oncoproteins targeted protein 1 (E6-targeted protein 1) is widely expressed and bound at the carboxy-terminus by Casein kinase I epsilon (CKIe) which leads to phosphorylation. SIPA1L1 activates RAP2A GTPase activity, aids reorganization of the actin cytoskeleton, recruits DLG4 to F-actin, regulates dendritic spine morphogenesis, and plays important roles in embryo development and cell proliferation.
~200 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes 2 isoforms at ~198 kDa and ~200 kDa
Immunogen
KLH-conjugated linear peptide corresponding to human SIPA1L1.
Application
Anti-SIPA1L1 Antibody is a highly specific rabbit polyclonal antibody, that targets Signal-induced proliferation associated-like protein 1 & has been tested in western blotting & IHC.
Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected SIPA1L1 in human brain tissue.
Analysis Note
Evaluated by Western Blotting in rat brain tissue lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected SIPA1L1 in 15µg of rat brain tissue lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| purified by | affinity chromatography |
| species reactivity | human, rat |
| technique(s) | immunohistochemistry: suitable,western blot: suitable |
| UniProt accession no. | O43166 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... SIPA1L1(26037) |
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