- 商品介绍
- 规格参数
- 包装参数
General description
A cell-permeable, xanthenyl compound that prevents mRNA-ribosome interaction and inhibits 5’-mediated/cap-dependent initiation of protein synthesis (>95% inhibition at 50 µM in in vitro translation assays using Krebs, rabbit reticulocyte, or E. coli S30 extract).
Biochem/physiol Actions
Cell permeable: yes
Primary Target
human arginine methyl transferase
Product does not compete with ATP.
Reversible: no
Target IC50: 1.41 µM against human arginine methyl transferase
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
Novac, O., et al. 2004. Nucleic Acids Res.32, 902.
Tan, Y.J., et al. 2003. J. Cancer Res. Clin. Oncol.129, 437.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
| Quality Level | 100 |
| assay | ≥95% (HPLC) |
| form | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze,protect from light |
| color | light brown |
| solubility | DMSO: 200 mg/mL,methanol: soluble |
| shipped in | ambient |
| storage temp. | 2-8°C |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |




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