- 商品介绍
- 规格参数
- 包装参数
General description
13.3 kDa
Galanin is a neuropeptide which is not a member of any known family of neuropeptides, despite repeated efforts to discover related peptides. Its actions are mediated via Gi-protein-coupled receptors (GPCR’s) and ion channels, usually producing inhibition of secretion of a transmitter or hormone in the nervous and endocrine system. In many respects, these inhibitory actions of galanin remind us of those of gamma-aminobutyric acid (GABA) and of neuropeptide Y (NPY). Galanin coexists with GABA, noradrenaline, 5-hydroxytryptamine (5-HT), and NPY in several regions of the brain. Galanin and it’s receptor are over expressed in limbic region of the brain in patients suffering from Alzheimer′s disease. However it is not clear whether galanin exacerbates or is a protective response to the disease.
Immunogen
Synthetic Linear Peptide
Application
Detect Galanin using this Anti-Galanin Antibody validated for use in IH(P).
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins
Biochem/physiol Actions
Cat. # AB2233 recognizes Galanin
Reactivity with other species has not been determined.
Physical form
Serum with 0.05% NaN3
Preparation Note
Maintain at -20°C for up to 1 year from date of receipt.
Analysis Note
Control
Rat Cerebellum Tissue
Routinely evaluated by Immunhistochemistry on rat cerebellum tissue.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | serum |
| antibody product type | primary antibodies |
| clone | polyclonal |
| species reactivity | rat |
| species reactivity (predicted by homology) | mouse, boar, human |
| technique(s) | immunohistochemistry: suitable (paraffin) |
| NCBI accession no. | NP_057057 |
| UniProt accession no. | P22466 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... GAL(51083) |
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| 重量(kg) |
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