- 商品介绍
- 规格参数
- 包装参数
General description
Junctophilin-3 (JPH3, JP-3), also known as Trinucleotide repeat-containing gene 22 protein (TNRC22), is a single-pass type IV membrane protein belonging to the junctophilin family. Junctophilins are important components of the junctional complexes which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. JPH3 is specifically expressed in brain. A mutation associated with JPH3 is the cause of Huntington disease-like type 2 (HDL2), a neurodegenerative disorder.
~105 kDa observed. Uniprot describes 2 isoforms at ~20 kDa and ~81 kDa Uncharacterized bands may appear in some lysates.
Immunogen
Epitope: Near C-terminus.
KLH-conjugated linear peptide corresponding to a sequence near the C-terminus of human JPH3.
Application
Anti-JPH3 Antibody is a highly specific rabbit polyclonal antibody, that targets Junctophilin-3 & has been tested in western blotting, IHC & Immunofluorescence.
Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected JPH3 in human brain tissue.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected JPH3 in human brain cells.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Biochem/physiol Actions
This antibody recognizes the C-terminus of JPH3.
Physical form
Affinity purified.
Purified rabbit polyclonal antibody in buffer containing PBS with 0.02% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
Daudi cell lysate
Evaluated by Western Blotting/Peptide Inhibition Assay in Daudi cell lysate.
Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected JPH3 in 15 µg of Daudi cell lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| purified by | affinity chromatography |
| species reactivity | human |
| technique(s) | immunofluorescence: suitable,immunohistochemistry: suitable,western blot: suitable |
| UniProt accession no. | Q8WXH2 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... JPH3(57338) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
¥ 9207.92
-
¥ 3109.49
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
¥ 238.17
-
¥ 3812.28
-
¥ 2268.97
-
¥ 1509.00
-
¥ 5014.59
-
¥ 3896.11
-
¥ 2911.61
-
¥ 5804.96
-
NALGENE 180透明塑料管，透明，柔软，多用，经济，内径 x 外径x壁厚，1/8 x 1/4 x 1/16，英寸，每箱数量50，50/箱，8000-0020，Thermofisher，赛默飞世尔询价
-
¥ 37675.92
微信小程序
7X24小时在线咨询