- 商品介绍
- 规格参数
- 包装参数
General description
Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
~17 kDa observed
Application
Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected dimethyl Histone H3 (Arg26), Asymmetric in A431 and HepG2 cells.
Dot Blot (Specificity) Analysis: 0.5 µg/mL from a representative lot detected dimethyl Histone H3 (Arg26), Asymmetric in Absurance
DyLight
This Anti-dimethyl Histone H3 (Arg26) antibody, Asymmetric is validated for use in western blotting, ICC & dot blot for the detection of dimethyl Histone H3 (Arg26).
Biochem/physiol Actions
Broad species reactivity is expected based on immunogen sequence similarities.
Analysis Note
Evaluated by Western Blotting in untreated and CARM1 treated HeLa acid extracts.
Western Blotting Analysis: 1 µg/mL of this antibody detects dimethyl Histone H3 (Arg26), Asymmetric in 10 µg of CARM1 treated HeLa acid extract.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
| biological source | rabbit |
| Quality Segment | 100 |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| purified by | affinity chromatography |
| species reactivity | human |
| technique(s) | dot blot: suitable,immunocytochemistry: suitable,western blot: suitable |
| NCBI accession no. | NP_003520 |
| UniProt accession no. | P68431 |
| shipped in | wet ice |
| target post-translational modification | dimethylation (Arg26) |
| Gene Information | human ... HIST1H3F(8968) |
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¥ 2814.26
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