Anti-Sphingosine 1-phosphate receptor 5 (S1P5) Antibody, clone 13F9.1,100UG,MABC98,Sigma

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订货号 0BV9986
品牌型号 Sigma MABC98
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Sphingosine 1-phosphate receptor 5 (S1PR5 or S1P5), otherwise known as EDG8, is a G-protein coupled receptor which is activated by the lysosphingolipid sphingosine 1-phosphate (S1P). It is coupled to Gi/0 alpha and G12 signaling pathways. S1P5 is highly abundant in the brain, particularly in the corpus callosum, but S1P5 has also been detected in the spleen, placenta, lung, aorta, and peripheral blood leukocytes. In the brain, it regulates the transformation of radial glial cells into astrocytes, and the migration of oligodendrocyte precursor cells during development.
~42 kDa observed


Immunogen

Recombinant protein corresponding to mouse Sphingosine 1-phosphate receptor 5 (S1P5).


Application

Detect Sphingosine 1-phosphate receptor 5 (S1P5) using this Anti-Sphingosine 1-phosphate receptor 5 (S1P5) Antibody, clone 13F9.1 validated for use in Western Blotting & IHC.
Immunohistochemistry Analysis: A 1:300 dilution from a representative lot detected Sphingosine 1-phosphate receptor 5 in normal human cerebellum and normal placenta tissue.


Physical form

Format: Purified


Analysis Note

Evaluated by Western Blot in Daudi cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected Sphingosine 1-phosphate receptor 5 in 10 µg of Daudi cell lysate.


Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone13F9.1, monoclonal
species reactivityhuman
species reactivity (predicted by homology)mouse (immunogen homology)
technique(s)immunohistochemistry: suitable,western blot: suitable
isotypeIgG1κ
NCBI accession no.NP_001159687
UniProt accession no.Q9H228
shipped inwet ice
target post-translational modificationunmodified
Gene Informationhuman ... S1PR5(53637)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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