Anti-Lefty Antibody, clone 1G9.1,100UG,MABD146,Sigma

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订货号 0BV9994
品牌型号 Sigma MABD146
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Left-right determination factor 1 (LEFTY1) also known as Left-right determination factor B, Protein lefty-1, Protein lefty-B, and encoded by the gene name LEFTYB, LEFTY1, LEFTB, is a member of the the TGF-beta family. LEFTY1 collaborates with other members of the TGFβ (Transforming Growth Factor) family to establish a left-right axis that dictates the asymmetrical distribution of internal organs during vertebrate embryogenesis. Mice deficient in LEFTY1 are affected by pulmonary isomerism and abnormal placement of vascular tracts, possibly the result of unregulated expression of LEFTY2 and NODAL.
~40 kDa observed


Immunogen

KLH-conjugated linear peptide corresponding to human Lefty and spans the pro and mature cleavage sites.


Application

Anti-Lefty Antibody, clone 1G9.1 | MABD146 is an antibody against Lefty Antibody for use in Western Blotting.
Research Category
Stem Cell Research
Research Sub Category
Cell Cycle, DNA Replication & Repair
Western Blotting Analysis: 0.5 µg/mL from a representative lot detected Lefty in 10 µg of C2C12 and NIH-3T3 cell lysate.


Physical form

Format: Purified
Purified by Ion-Exchange Chromatography
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.


Preparation Note

Stable for 1 year at 2-8°C from date of receipt.


Analysis Note

Evaluated by Western Blotting in L6 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Lefty in 10 µg of L6 cell lysate.


Other Notes

Concentration: Please refer to lot specific datasheet.
Replaces: MABD186


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified antibody
antibody product typeprimary antibodies
clone1G9.1, monoclonal
species reactivityrat, mouse
technique(s)western blot: suitable
isotypeIgMκ
NCBI accession no.NP_066277
UniProt accession no.O75610
shipped inwet ice
target post-translational modificationunmodified
Gene Informationhuman ... LEFTY1(10637)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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