- 商品介绍
- 规格参数
- 包装参数
General description
Catalyzes the isomerization of peroxynitrite (ONOO–) to nitrate (NO3–) under physiological conditions and at realistic dose-derived concentrations (Kcat = 2.2 x 106 M-1s-1). Effectively prevents the oxidation of lipid components by peroxynitrite. Also catalytically decomposes superoxide radicals (O2·). Irradiation of the aqueous solution at 335 nm releases hydroxyl (OH·) radicals. FeTMPyP can also serve as a potential for drug detoxification of reactive oxygen species (ROS).
Biochem/physiol Actions
Cell permeable: no
Kcat = 2.2 x 106 M-1s-1 in catalyzing the isomerization of peroxynitrite (ONOO-) to nitrate (NO3-) under physiological conditions
Primary Target
Peroxynitrite (ONOO-)
Product does not compete with ATP.
Reversible: no
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
Other Notes
Lee, J., et al. 1998. J. Am. Chem. Soc. 120, 7493.
Hunt, J.A., et al. 1997. Chem. Biol. 4, 845.
Marla, S.S., et al. 1997. Proc. Natl. Acad. Sci. USA 94, 14243.
Stern, M.K., et al. 1996. J. Am. Chem. Soc. 118, 8735.
Faraggi, M., et al. 1984. Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med.46, 703.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
| Quality Level | 100 |
| assay | ≥90% (TLC) |
| form | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze,desiccated (hygroscopic),protect from light |
| color | brown |
| solubility | water: 50 mg/mL |
| shipped in | ambient |
| storage temp. | −20°C |
| 长度(mm) | |
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¥ 3275.78
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¥ 3372.68
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¥ 6330.00
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瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmPES滤膜，孔径0.45um,适合瓶颈尺寸33mm，12/箱，295-3345，Nalgene，Thermofisher，赛默飞世尔¥ 1938.54
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¥ 14407.09
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¥ 2882.02
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¥ 745.60
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¥ 1301.36
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¥ 3852.13
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¥ 8137.12
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