Anti-Limk1 Antibody, clone 6C3.1| MABN118,100UG,MABN118,Sigma

销售价: ¥ 4558.99 / 件
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订货号 0BW0263
品牌型号 Sigma MABN118
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

LIM Kinase 1 (LIMK1) is a protein kinase that plays an important role in cellular functions like cell motility and growth cone actin dynamics. LIMK1 contains one PDZ domain and two LIM domains which mediate protein to protein inteactions. It is widely expressed in the adult and fetal nervous system with the highest levels being found in the cerebral cortex. Mutations in LIMK1 have been associated with cardiovascular and musculo-skeletal abnormalities.
~72 kDa observed


Immunogen

GST-tagged recombinant protein corresponding to human Limk1.


Application

Detect Limk1 using this Anti-Limk1 Antibody, clone 6C3.1 validated for use in western blotting & IHC.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Limk1 in human thalamus and human cerebral cortex tissue.


Physical form

Format: Purified


Analysis Note

Evaluated by Western Blotting in human cortex tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected Limk1 in 10 µg of human cortex tissue lysate.


Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone6C3.1, monoclonal
species reactivityhuman
technique(s)immunohistochemistry: suitable,western blot: suitable
isotypeIgG1κ
NCBI accession no.NP_002305
UniProt accession no.P53667
shipped inwet ice
target post-translational modificationunmodified
Gene Informationhuman ... LIMK1(3984)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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