- 商品介绍
- 规格参数
- 包装参数
General description
Neurotrophin4 (NT4), also known as NT5, is a member of the NGF family of neuronal and epithelial growth factors. NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).
Biochem/physiol Actions
Cross Reactivty
Mouse, Rat
Physical form
Recombinant animal free human NT-4 is manufactured using all non-animal reagents
Analysis Note
Bioactivity assay: The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found in the range of 20-50 ng/ml.
| Quality Segment | 100 |
| assay | >98% (SDS-PAGE and HPLC) |
| impurities | <0.1 μg/mg protein endotoxin (<1EU/μg) |
| NCBI accession no. | NM_006179.3 |
| UniProt accession no. | P34130 |
| shipped in | dry ice |
| storage temp. | -10 to -25°C |
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¥ 2528.88
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¥ 1259.40
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¥ 2019.57
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¥ 3109.49
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¥ 3290.05
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¥ 2883.61
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¥ 4897.21
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¥ 14407.09
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¥ 10277.12
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¥ 8982.64
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¥ 2617.87
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