- 商品介绍
- 规格参数
- 包装参数
General description
37kDa
TorsinA can regulate the cellular trafficking of the dopamine transporter, as well as other polytopic membrane-bound proteins, including G protein-coupled receptors, transporters, and ion channels. TorsinA is found in the dopamine neurons that are lost in PD, and is a component of Lewy bodies. in addition, a genetic defect in TorsinA underlies Torsion dystonia, a disease characterized by painful muscle contractions that result in uncontrollable distortions.
Immunogen
Maltose binding protein fusion protein from human torsinA.
Application
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience
Neurodegenerative Diseases
This Anti-TorsinA Antibody is validated for use in IP, WB, IC for the detection of TorsinA.
Biochem/physiol Actions
TorsinA
Physical form
Ascites
Liquid. Contaings no preservative
Preparation Note
Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.
Analysis Note
Control
Positive Control: Human brain lysate, NGF treated PC12 cells.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | ascites fluid |
| antibody product type | primary antibodies |
| clone | monoclonal |
| species reactivity | mouse, rat, human |
| manufacturer/tradename | Chemicon® |
| technique(s) | immunocytochemistry: suitable,immunoprecipitation (IP): suitable,western blot: suitable |
| isotype | IgG1 |
| NCBI accession no. | NM_000113.2 |
| UniProt accession no. | O14656 |
| shipped in | dry ice |
| target post-translational modification | unmodified |
| Gene Information | human ... TOR1B(27348) |
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