Anti-HJURP Antibody, clone 144K/B1，100UG，MABE441，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

Holliday junction recognition protein (HJURP) is also known as 14-3-3-associated AKT substrate (FAKTS), Fetal liver-expressing gene 1 protein (FLEG1) and Up-regulated in lung cancer 9 (URLC9). HJURP is a centromeric protein that acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. HJURP is highly expressed in the thymus, testis, and in many lung cancer samples with lower levels found in placenta, small intestine, liver, skeletal muscle, and colon.
~90 kDa observed

Immunogen

Recombinant protein corresponding to human HJURP.

Application

Detect Holliday junction recognition protein using this mouse monoclonal antibody, Anti-HJURP Antibody, clone 144K/B1 validated for use in western blotting & IP.
Immunoprecipitation Analysis: A representative lot immunoprecipitated HJURP in HeLa nuclear extract (Ana Losada, CNIO, Madrid, Spain).

Chromatin Immunoprecipitation (ChIP) Analysis: A representative lot immmunoprecipitated HJURP in HEK293 cell lysate (Ana Losada, CNIO, Madrid, Spain).

Physical form

Format: Purified

Analysis Note

Evaluated by Western Blotting in HEK293 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected HJURP in 10 µg of HEK293 cell lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

技术参数 Specifications

biological source	mouse
Quality Segment	100
conjugate	unconjugated
antibody form	purified antibody
antibody product type	primary antibodies
clone	144K/B1, monoclonal
species reactivity	human
technique(s)	ChIP: suitable,immunoprecipitation (IP): suitable,western blot: suitable
isotype	IgG2bκ
NCBI accession no.	NP_060880.3
UniProt accession no.	Q8NCD3
shipped in	wet ice
target post-translational modification	unmodified
Gene Information	human ... HJURP(55355)

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